{"id":7464,"date":"2020-11-24T14:05:37","date_gmt":"2020-11-24T13:05:37","guid":{"rendered":"https:\/\/kunden.cayou-media.de\/gampt\/?p=7464"},"modified":"2023-05-22T14:08:19","modified_gmt":"2023-05-22T12:08:19","slug":"risk-free-intracranial-pressure-measurement-with-ultrasound","status":"publish","type":"post","link":"https:\/\/www.gampt.de\/en\/2020\/11\/24\/risk-free-intracranial-pressure-measurement-with-ultrasound\/","title":{"rendered":"Risk-free intracranial pressure measurement with ultrasound"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.20.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.20.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.20.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.20.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p><span lang=\"en-US\">In collaboration with the research team of the Institute of Radiology at the Charit\u00e9 Berlin led by Prof. Ingolf Sack, GAMPT is developing new medical diagnostic methods (THED) for the non-invasive examination of organs using the time-harmonic elastography method (THE).<\/span><\/p>\n<p><span lang=\"en-US\">Recently, the research team was able to measure the cerebral stiffness. Until now, this diagnosis could only be achieved using the risky pressure measurement of the cerebral fluid by drilling a hole into the cranial cavity. The physiological mechanisms leading to the change in stiffness are attributed to the cerebral-vascular reactivity, cerebral blood flow activity and intracranial regulation.<\/span><\/p>\n<p><span lang=\"en-US\">The results of the pilot study were published in the following articles:<\/span><\/p>\n<p><a href=\"https:\/\/www.umbjournal.org\/article\/S0301-5629(19)31639-4\/pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Time-Resolved Response of Cerebral Stiffness to Hypercapnia in Humans<\/a><br \/>Kreft B, Tzsch\u00e4tzsch H, Schrank F, Bergs J, Streitberger KJ, W\u00e4ldchen S, Hetzer S, Braun J, Sack I., Ultrasound Med Biol. 2020 Apr;46(4):936-943. doi: 10.1016\/j.ultrasmedbio.2019.12.019. Epub 2020 Jan 28<\/p>\n<p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30559367\/\" target=\"_blank\" rel=\"noopener noreferrer\">In vivo time-harmonic ultrasound elastography of the human brain detects acute cerebral stiffness changes induced by intracranial pressure variations<\/a><br \/>Tzschatzsch, H., Kreft, B., Schrank, F., Bergs, J., Braun, J. &amp; Sack, I., Sci Rep 8, 17888, doi:10.1038\/s41598-018-36191-9 (2018).<\/p>\n<p><span lang=\"en-US\">If you are interested in the publications, please contact:\u00a0<\/span><a href=\"mailto:ingolf.sack@charite.de\">ingolf.sack@charite.de<\/a><\/p>\n<p><span lang=\"en-US\">The mentioned measurement technology is commercially available for clinical research teams.\u00a0<\/span><span lang=\"en-US\">For details please contact<\/span>:\u00a0<a href=\"mailto:Grit.Oblonczek@gampt.de\">Dr. Grit Oblonczek<\/a><\/p>\n<p>[\/et_pb_text][et_pb_gallery gallery_ids=&#8221;7458,7460&#8243; _builder_version=&#8221;4.20.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In collaboration with the research team of the Institute of Radiology at the Charit\u00e9 Berlin led by Prof. Ingolf Sack, GAMPT is developing new medical diagnostic methods (THED) for the non-invasive examination of organs using the time-harmonic elastography method (THE).<\/p>\n","protected":false},"author":1,"featured_media":7459,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"<p>[et_pb_section fb_built=\"1\" theme_builder_area=\"post_content\" _builder_version=\"4.20.0\" _module_preset=\"default\"][et_pb_row _builder_version=\"4.20.0\" _module_preset=\"default\" theme_builder_area=\"post_content\"][et_pb_column _builder_version=\"4.20.0\" _module_preset=\"default\" type=\"4_4\" theme_builder_area=\"post_content\"][et_pb_text _builder_version=\"4.20.0\" _module_preset=\"default\" theme_builder_area=\"post_content\" hover_enabled=\"0\" sticky_enabled=\"0\"]<\/p><p>n Zusammenarbeit mit dem Forscherteam der Radiologie der Charit\u00e9 unter Leitung von Prof. Ingolf Sack entwickelt die Firma GAMPT mbH neue medizinische Diagnosemethoden (THED), welche mit dem Verfahren der zeitharmonischen Elastographie (THE) nicht-invasiv Organe untersuchen k\u00f6nnen. Zuletzt gelang es die Steifigkeit des Hirns zu messen. Bisher erfolgt diese Diagnose per risikobehafteter Druckmessung der Hirnfl\u00fcssigkeit durch Bohrung in die Sch\u00e4delh\u00f6hle. Die physiologischen Mechanismen, welche zu einer Steifigkeits\u00e4nderung f\u00fchren, werden der zerebral-vaskularen Reaktion, der Hirnflussaktivit\u00e4t und der intrakraniellen Regulierung zugeschrieben.<\/p><p>Die Ergebnisse einer Pilotstudio wurden in folgenden Artikeln publiziert:<br \/><a href=\"https:\/\/www.umbjournal.org\/article\/S0301-5629(19)31639-4\/pdf\" target=\"_blank\" rel=\"noopener noreferrer\">Time-Resolved Response of Cerebral Stiffness to Hypercapnia in Humans<\/a><br \/>Kreft B, Tzsch\u00e4tzsch H, Schrank F, Bergs J, Streitberger KJ, W\u00e4ldchen S, Hetzer S, Braun J, Sack I., Ultrasound Med Biol. 2020 Apr;46(4):936-943. doi: 10.1016\/j.ultrasmedbio.2019.12.019. Epub 2020 Jan 28<\/p><p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30559367\/\" target=\"_blank\" rel=\"noopener noreferrer\">In vivo time-harmonic ultrasound elastography of the human brain detects acute cerebral stiffness changes induced by intracranial pressure variations<\/a><br \/>Tzschatzsch, H., Kreft, B., Schrank, F., Bergs, J., Braun, J. & Sack, I., Sci Rep 8, 17888, doi:10.1038\/s41598-018-36191-9 (2018).<\/p><p>Bei Interesse an den Publikationen wenden Sie sich bitte an:\u00a0<a href=\"mailto:ingolf.sack@charite.de\">ingolf.sack@charite.de<\/a><\/p><p>Die genannte Messtechnik ist f\u00fcr Forschungsteams im klinischen Bereich kommerziell verf\u00fcgbar.<br \/>F\u00fcr Details kontaktieren Sie bitte:\u00a0<a href=\"mailto:Grit.Oblonczek@gampt.de\">Dr. Grit Oblonczek<\/a><\/p><p>[\/et_pb_text][et_pb_gallery _builder_version=\"4.20.0\" _module_preset=\"default\" gallery_ids=\"7458,7460\" theme_builder_area=\"post_content\" hover_enabled=\"0\" sticky_enabled=\"0\"][\/et_pb_gallery][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>","_et_gb_content_width":"","inline_featured_image":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1,90],"tags":[],"class_list":["post-7464","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news-en","category-news-2020-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Risk-free intracranial pressure measurement with ultrasound &#187; GAMPT mbH<\/title>\n<meta name=\"description\" content=\"Risk-free intracranial pressure measurement with ultrasound &#187; GAMPT mbH\" \/>\n<meta name=\"robots\" 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